A287 : by Tony Garland
Although I haven’t run across that suggestion in my reading on the subject, there's nothing that I’m aware of in the Scriptures that would absolutely preclude the idea.
Some commentators see Zechariah 11:17 as a possible indication of how the Antichrist will be either wounded or possibly killed. But it is impossible to be dogmatic on that point.
If the witnesses were to kill the Antichrist, then it would be a somewhat strange turn-around of events for him to rise and overthrow them after being overthrown by them. Even so, as I said, I'm not aware of a passage that would preclude this idea. What we can say is that he appears to have been killed—prior to his restoration and ascension from the abyss to subsequently kill the witnesses (Rev. 11:7).
Having said that, I would caution not to go beyond what Scripture reveals as it tends to fuel speculation. Many students and teachers of God’s Word wind up with strange ideas and doctrines by placing too much emphasis upon vague passages, sensational ideas, and speculation rather than sticking to what Scripture clearly reveals.
Paying attention to what is not explicitly stated in Scripture is sometimes as important as studying what is. 
There is more than a life-time of things that are revealed within Scripture to keep us busy without having to go beyond that. So, it might be an interesting idea to think about, but I don't think one can go very far with it.
Thanks for your interest.
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